产品信息
| 别名 | Granulocyte colony-stimulating factor; Csf3; G-CSF |
| 物种 | Mouse |
| 表达宿主 | Human Cells |
| 序列信息 | Val31-Ala208 |
| 检索号 | P09920 |
| 分子量 | 19.8 kDa |
| 表观分子量 | 25 kDa |
| 标签 | C-6His |
产品特性
| 纯度 | >95% as determined by reducing SDS-PAGE. |
| 内毒素 | <1.0 EU per µg as determined by LAL test. |
| 保存 | Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months. |
| 运输 | Ambient temperature or ice pack. |
| 制剂 | Lyophilized from a 0.2 μm filtered solution of 10mM Sodium Citrate, 0.1% Tween 20, pH 3.5. |
| 复融 | Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
背景介绍
Granulocyte colony-stimulating factor (G-CSF) is a Growth Factor and an essential Cytokine which belongs to the IL-6 superfamily. Granulocyte/ macrophage colony-stimulating factors are Cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. G-CSF binding to its Receptor G-CSF-R which belongs to the Cytokine Receptor type I family depends on the interaction of alpha-helical Motifs of the former and two fibronectin type III as well as an immunoglobulin-like domain of the latter. G-CSF is a Cytokine that have been demonstrated to improve cardiac function and perfusion in myocardial infarction. And it was initially evaluated as a stem cell mobilizer and erythropoietin as a cytoprotective agent.
