本司产品仅用于科研,不用于临床诊断和治疗

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MEC/ CCL28, Human, Recombinant

货号:PCK113

价格:¥1480¥3980¥1388019980

规格:
10µg
  • 10µg
  • 50µg
  • 500µg
  • 1mg
数量: - +

产品信息

别名 C-C Motif Chemokine 28; Mucosae-Associated Epithelial Chemokine; MEC; Protein CCK1; Small-Inducible Cytokine A28; CCL28; SCYA28
物种 Human
表达宿主 E.coli
序列信息 Ser20-Tyr127
检索号 Q9NRJ3
分子量 12.49 kDa
表观分子量 15 kDa

产品特性

纯度 >95% as determined by reducing SDS-PAGE.
内毒素 < 1.0 EU per µg as determined by LAL test.
保存 Lyophilized protein should be stored at -5~-20℃, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at -5~-20℃ for 3 months.
运输 Ambient temperature or ice pack.
制剂 Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
复融 Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in distilled water.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

背景介绍

Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel Chemokine that shares the most homology with CCL27/ CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner. CCR10 (GPR2 orphan Receptor) is also the Receptor for CCL27/ CTACK. CCL28 is preferentially expressed by epithelial cells of diverse tissues, with highest expression level in normal and pathological colon. It is also expressed in normal and asthmatic lung tissues. Human and mouse CCL28 shares 83% sequence identity in their mature regions.
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