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IFNω/IFN alpha II-1/IFNW1, Human, Recombinant

货号:PCK281

价格:¥480¥¥

规格:
10μg
  • 10μg
数量: - +

产品信息

别名 IFN alpha II-1, IFNW1
物种 Human
表达宿主 E.coli
序列信息 MCDLPQNHGLLSRNTLVLLHQMRRISPFLCLKDRRDFRFPQEMVKGSQLQKAHVMSVLHEMLQQIFSLFHTERSSAAWNMTLLDQLHTGLHQQLQHLETCLLQVVGEGESAGAISSPALTLRRYFQGIRVYLKEKKYSDCAWEVVRMEIMKSLFLSTNMQERLRSKDRDLGSS with polyhistidine tag at the C-terminus.
检索号 P05000.2
分子量 20.93 kDa
表观分子量 20 kDa
标签 His-tag at the C-terminus
生物活性 Measure by its ability to induce cytotoxicity in TF-1 cells.The ED50 for this effect is <0.02 ng/mL.The specific activity of recombinant human IFN omega is approximately >5 x10^7 IU/ mg.

产品特性

纯度 >95% as determined by SDS-PAGE. Ni-NTA chromatography.
内毒素 <0.1 EU per 1 μg of the protein by the LAL method.
保存 Lyophilized protein should be stored at -5~-20°C for 1 year. Upon reconstitution, store at 2-8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g.0.1%BSA,10%FBS,5%HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20°C or -80°C for 3-6 months.
运输 Ambient temperature or ice pack.
制剂 The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4.
复融 It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL.Do Not Vortex! Vigorous shaking may impair the biological activity of the protein.

背景介绍

IFN-ω is a member of the type I interferon family, that can be induced by virus infected leukocytes and exert antiviral and anti-proliferative activities. IFN-ω shares about 75% sequence homology with IFN-α. There are two conserved disulfide bonds that are necessary for full biological activity.
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