产品信息
| 别名 | LGALS8, Gal-8, PCTA-1, PCTA1, Po66-CBP |
| 物种 | Human |
| 表达宿主 | E.coli |
| 序列信息 | MLSLNNLQNIIYNPVIPFVGTIPDQLDPGTLIVIRGHVPSDADRFQVDLQNGSSMKPRADVAFHFNPRFKRAGCIVCNTLINEKWGREEITYDTPFKREKSFEIVIMVLKDKFQVAVNGKHTLLYGHRIGPEKIDTLGIYGKVNIHSIGFSFSSDLQSTQASSLELTEISRENVPKSGTPQLRLPFAARLNTPMGPGRTVVVKGEVNANAKSFNVDLLAGKSKDIALHLNPRLNIKAFVRNSFLQESWGE |
| 检索号 | O00214.4 |
| 分子量 | 36.6 kDa |
| 表观分子量 | 34 kDa |
| 标签 | His-tag at the N-terminus |
| 生物活性 | Measured by its ability to agglutinate human red blood cells.The ED50 for this effect is <8 μg/mL. |
产品特性
| 纯度 | >98% as determined by SDS-PAGE. Ni-NTA chromatography |
| 内毒素 | <0.1 EU per 1 μg of the protein by the LAL method. |
| 保存 | Lyophilized protein should be stored at -5~-20°C for 1 year. Upon reconstitution, store at 2-8°C for up to 1 week. Further dilute in a buffer containing a carrier protein or stabilizer (e.g.0.1%BSA,10%FBS,5%HSA or 5% trehalose solution), protein aliquots should be stored at -5~-20°C or -80°C for 3-6 months. |
| 运输 | Ambient temperature or ice pack. |
| 制剂 | The protein was lyophilized from a 0.2 µm filtered solution containing 1X PBS, pH 7.4. |
| 复融 | It is recommended to reconstitute the lyophilized protein in sterile water to a concentration not less than 100 μg/mL.Do Not Vortex! Vigorous shaking may impair the biological activity of the protein. |
背景介绍
Galectin-8(LGALS8), a member of the galectin gene family, is identified to specifically express in prostate , and is espacially overexpressed in malignant tumors, thereby can be used as an extra specific identifier of malignancies. The gene encoded protein facilitates both cell-cell and cell matrix interactions in a method parallel to the selectin subgroup of C-type lectins.
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